Allergies and Skin Sensitivities
Understanding Type I and Type IV Reactions Related to Gloves
Type I latex allergy is an immediate allergic reaction associated with natural rubber latex proteins. Type IV allergic contact dermatitis is a delayed skin reaction that may be associated with residual chemicals used in the manufacture of some rubber products, including certain vulcanisation accelerators.
Because these reactions have different causes, glove selection should be based on the user’s known sensitivity, the glove material, product composition, intended use, and available product documentation.
Type I Latex Allergy
For users with a known or suspected Type I latex allergy, latex-free glove alternatives should be considered. If symptoms occur, users should seek medical advice and follow the recommendations of their occupational health or medical specialist.
Type IV Allergic Contact Dermatitis
Type IV allergic contact dermatitis is a delayed skin reaction that may appear hours or days after exposure. Symptoms may include redness, itching, dryness, scaling, or blistering.
In glove use, Type IV reactions are often associated with sensitisation to residual chemicals, including certain vulcanisation accelerators used in the production of some rubber gloves. The relevance of individual substances may vary by user and product formulation.
The new EN 455-5:2025 standard provides a test method for measuring extractable chemical residues in single-use medical gloves, particularly substances associated with Type IV allergenic potential. This supports a more structured approach to assessing residual chemicals in medical gloves.
How HARPS Global Supports Skin-Friendly Glove Selection
For natural rubber latex gloves, manufacturing processes can help reduce extractable latex proteins and residual substances. For users with known sensitivities, alternative glove materials or formulations may be more suitable.
No glove can eliminate the risk of skin reactions for every user. Users with known allergies or persistent skin symptoms should consult a medical or occupational health specialist and select gloves based on individual needs and product-specific information.
Learn more about Our DPG-Free Products
In recent years, both the latex protein content and the chemical residues have been reduced significantly through new methods in glove production. Moreover, new vulcanisation accelerators have been developed that are significantly more tolerable and do not have any residues that are easily released.
Learn more about skin-friendly glove alternatives
Get in contact with our experts and find the right glove for your needs.